Ukufunyanwa okutsha! I-Xenon inhalation inokunyanga ngokufanelekileyo isithsaba esitsha sokuphefumla

Kutshanje, abaphandi kwiZiko le-Pharmacology kunye ne-Regenerative Medicine ye-Tomsk National Research Medical Centre ye-Russian Academy of Sciences bafumanisa ukuba ukuphefumlaxenonIrhasi inokunyanga ngokufanelekileyo ukungasebenzi kwe-pulmonary ventilation, kwaye iphuhlise isixhobo sokwenza umsebenzi ngokufanelekileyo. Itekhnoloji entsha yahlukile kwihlabathi jikelele kwaye inexabiso eliphantsi kakhulu.

Ukusilela kokuphefumla kunye nesiphumo se-hypoxemia (iimpawu ezibukhali ze-COVID-19 okanye iimpawu zasemva kwe-COVID-19) okwangoku zinyangwa ngonyango lwe-oxygen,i-nitric oxide, i-helium, i-exogenous surfactants, kunye ne-antiviral kunye ne-anticytokine amachiza ahlukeneyo ahlukeneyo zonyango. Nangona kunjalo, ukusebenza kwezi ndlela kuvuleleke ukuba kuxoxwe.

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U-Vladimir Udut, MD, usekela-mlawuli we-Institute of Pharmacology kunye ne-Regenerative Medicine kwi-Tomsk National Research Medical Centre, uthe ukwenza inkqubo eyandisa i-oxygen saturation yegazi kufuna ukuqonda ukuba le mpembelelo iphunyezwa njani. kwaye uqonde iindlela eziphucula ukunikezelwa kweoksijini xa imiphunga yonakele.

Ekupheleni kuka-2020, abaphandi kwiYunivesithi yaseTomsk bafumanisa ukuba abaguli abosulelwe yi-coronavirus entsha kwaye bakhula ukuphazamiseka kwengqondo kwaye baziva uxinzelelo olukhulu baye bawuphucula kakhulu umsebenzi wokuphefumla emvaxenonunyango lokuphefumla.

Xenonyigesi enqabileyo, kwaye i-xenon yikhemikhali yokugqibela kwithuba lesihlanu letheyibhile yeperiodic. Ngenxa ye-tropism (i-attachment) kwii-receptors ezininzi ezithile,xenoninokulawula i-excitability yezicubu ze-nerve, kwaye idlale i-hypnotic kunye ne-anti-stress effect, ngaloo ndlela ikhusela izifo ze-neurological.

Abaphandi bafumanise ukuba ngenxaxenonIsakhono esisodwa sokubuyisela utshintshiselwano lwerhasi phakathi kwe-alveoli kunye neecapillaries kunye nomsebenzi we-surfactant (into edibanisa i-alveoli kwaye ikhusela i-alveoli ekuvaleni ngenxa yoxinzelelo oluphantsi lomphezulu ngexesha lokuphefumla), ukuze kuphunyezwe isiphumo sonyango. Ngele ndlela,xenoni-inhalation idala iimeko eziyimfuneko zokudluliselwa kwe-oksijini kwi-air inhaled ukuya egazini, umphumo onokubonakala kunye ne-pulse oximeters eqhelekileyo.

U-Udut uthe okwangoku, akukho teknoloji efanayo ekusebenzeni kwehlabathi, kwaye isixhobo sokuphefumla sinokuveliswa ngeprinta ye-3D ngexabiso eliphantsi. I-Hypoxemia ngexesha lokungaphumeleli kokuphefumla ibangela uxinzelelo kwaye ngaloo ndlela idideke. Uxinzelelo kunye ne-delirium inokuthintelwa ngokuphelisa ukungasebenzi kakuhle kokungena komoya emiphungeni ngexenonigesi.


Ixesha lokuposa: Dec-28-2022