Ekuqaleni kweminyaka engama-2025, abaphandi abavela kwiDyunivesithi yaseWashington noBrigham kunye nesibhedlele sabafazi (isibhedlele sesikolo saseHarvard) batyhila indlela engazange ibonwe i-AlzheimerI-XenonIrhasi, engathintela kuphela i-neuroinflam kwaye inciphise i-atrophy yengqondo, kodwa inyuse i-Neuronal Councinal States.

I-Xenonkunye ne-neuroprotection

Isifo sika-Alzheimer sesona sifo sixhaphakileyo esixhaphakileyo ebantwini, kwaye unobangela wayo ukholelwa ukuba unxulumene nokuqokelelwa kweproteni ye-TAU kunye neProtein ye-Beta-Amyloid kwingqondo. Nangona kukho iziyobisi ezazizama ukususa ezi proteni zetyhefu, azizange ziphumelele ekuqhubekisweni kwesi sifo. Ke ngoko, akukho ngcazulu yeso sifo okanye unyango luqondwe ngokupheleleyo.

Izifundo zibonisileI-XenonUngawela umqobo wegazi wegazi kwaye uphucule umgangatho weempuku ngemodeli yezifo ze-alzheimer phantsi kweemeko zelebhu.Uvavanyo lwahlulwa lwahlulwahlulwahlulwahlulwahlulwahlulwahlulwa, elinye iqela leempuku labonisa ukuqhutywa kweprotheni yeProtein kunye nelinye iqela laline-Beta-Amyloid iprotein protein. Iziphumo zovavanyo zibonisa ukuba i-Xenon ayizenzi iimpuku ezisebenzayo ngakumbi, kodwa ikwakhuthaza impendulo yokukhusela kwe-microglie, ebaluleke kakhulu ekucaciseni iiprotey ze-Tau kunye ne-Beta-Amyloid.

Le funyaniso intsha inenoveli kakhulu, ibonisa ukuba iziphumo ze-neuroproupective zinokuveliswa ngokuphefumla igesi ye-inter. Umda omkhulu kwicandelo lophando lophando luka-Alzheimer kukuba kunzima kakhulu ukuyila iziyobisi ezinokuthi ziwele umqobo wegazi, kwayeI-XenonUngayenza le nto.

Ezinye izicelo zonyango ze-Xenon

I-1. I-Anesthesia kunye neAnalGesia: Njengegesi efanelekileyo ye-anesthetic,I-Xenonisetyenziswa ngokubanzi ngenxa yokungeniswa okukhawulezayo kunye nokubuyisela kwakhona, uzinzo lwentliziyo elungileyo kunye nomngcipheko ophantsi weziphumo ebezingalindelekanga;

I-2. Ukongeza kwifuthe elinokubakho kwisifo se-Alzheimer ekhankanywe apha ngasentla, i-Xenon ifundwe nokunciphisa umonakalo wobuchopho obangelwe ngu-Nypoicy (Hie);

I-3. Ukufakelwa komntu kunye nokukhuselwa:I-XenonInganceda ukukhusela amathambo abanikeli kwi-IScheChemia-Reflousion yokulimala, ebaluleke kakhulu ekuphuculeni inqanaba lempumelelo lokuhanjiswa;

I-4. Imvakalelo yokuPhila ye-radiotherapy: Ezinye izifundo zangaphambili zibonise ukuba uXenon unokuphucula ubuntununtunu lwamathumba kwi-radiotherapy, ebonelela ngesicwangciso esitsha kunyango lomhlaza;